Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cns-5161 SCHEMBL499356 | 0.96 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Cns-5161 SCHEMBL29370312 | 0.96 | GRIN2D (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Cns-5161 SCHEMBL6420655 | 0.95 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14126031 | 0.89 | GRIN2D (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7202740 | 0.89 | GRIN2D (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6724095 | 0.89 | GRIN2D (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6717121 | 0.88 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6720705 | 0.88 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL12123177 | 0.88 | GRIN2D (0.46) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7208221 | 0.88 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759747-B2 | Alkylation method | GE HEALTHCARE LIMITED (GB) | 2020-09-01 | — | — | US | disclosed |
| US-20190161440-A1 | ALKYLATION METHOD | KINGS COLLEGE LONDON (GB) | 2019-05-30 | — | — | US | disclosed |
| WO-2017186969-A1 | ALKYLATION METHOD | GE HEALTHCARE LIMITED (GB) | 2017-11-02 | — | — | WO | disclosed |
| EP-2569279-B1 | METHOD OF SYNTHESIS | GE HEALTHCARE LTD (GB) | 2014-07-09 | — | — | EP | disclosed |
| US-8633337-B2 | Method and synthesis | GE HEALTHCARE LIMITED (GB) | 2014-01-21 | — | — | US | disclosed |
| US-8633337-B2 | Method and synthesis | GE HEALTHCARE LIMITED (GB) | 2014-01-21 | — | — | US | disclosed |
| EP-2569279-A1 | METHOD OF SYNTHESIS | GE Healthcare UK Limited (GB) | 2013-03-20 | — | — | EP | disclosed |
| US-20130060064-A1 | METHOD AND SYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2013-03-07 | — | — | US | disclosed |
| US-20130060064-A1 | METHOD AND SYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2013-03-07 | — | — | US | disclosed |
| WO-2011141568-A1 | METHOD OF SYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011141568-A1 | METHOD OF SYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2011-11-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759747-B2 | Alkylation method | INMT, ALKBH3, PIGO | GRIN2D 3331/4885GRIN3B 1939/4885GRIN1 3197/4885 |
| US-20190161440-A1 | ALKYLATION METHOD | INMT, ALKBH3, PIGO | GRIN2D 3331/4885GRIN3B 1939/4885GRIN1 3197/4885 |
| US-20130060064-A1 | METHOD AND SYNTHESIS | RNMT, GMPS, GDA | GRIN2D 1450/4885GRIN3B 899/4885GRIN1 2030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.