Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25939646 | 0.82 | EPHX2 (0.51) | TSHRAKR1C3AKR1C1MAPTNOTUM | |
| SCHEMBL17323628 | 0.82 | EPHX2 (0.51) | TSHRAKR1C3AKR1C1MAPTNOTUM | |
| SCHEMBL31066651 | 0.77 | TSHR (0.50) | TSHRAKR1C3AKR1C1MAPTNOTUM | |
| SCHEMBL27713735 | 0.77 | TSHR (0.50) | TSHRAKR1C3AKR1C1MAPTNOTUM | |
| SCHEMBL25939642 | 0.76 | TSHR (0.53) | TSHRAKR1C3AKR1C1MAPTNOTUM | |
| SCHEMBL3290728 | 0.76 | TSHR (0.53) | TSHRAKR1C3AKR1C1MAPTNOTUM | |
| SCHEMBL3282634 | 0.76 | TP53 (0.55) | TSHRAKR1C3AKR1C1MAPTPOLB | |
| SCHEMBL25939514 | 0.76 | TP53 (0.55) | TSHRAKR1C3AKR1C1MAPTPOLB | |
| SCHEMBL25939640 | 0.76 | TP53 (0.55) | TSHRAKR1C3AKR1C1MAPTPOLB | |
| SCHEMBL25939641 | 0.74 | ALDH1A1 (0.49) | TSHRAKR1C3AKR1C1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |