Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27045573 | 0.81 | F2 (0.47) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL2510973 | 0.80 | KMT2A (0.50) | LMNAF2TSHRTP53KMT2A | |
| SCHEMBL28495717 | 0.78 | HPGD (0.53) | LMNAF2TSHRTP53KMT2A | |
| SCHEMBL1249246 | 0.78 | HPGD (0.53) | LMNAF2TSHRTP53KMT2A | |
| SCHEMBL25796422 | 0.77 | F2 (0.47) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL25771035 | 0.77 | LMNA (0.47) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL1266020 | 0.77 | F2 (0.47) | LMNAF2TSHRTDP1TP53 | |
| SCHEMBL29098438 | 0.77 | HPGD (0.52) | LMNAF2TSHRTP53KMT2A | |
| SCHEMBL24120719 | 0.76 | SIGMAR1 (0.56) | LMNAF2TSHRKMT2AALDH1A1 | |
| SCHEMBL226315 | 0.76 | KMT2A (0.55) | LMNATSHRKMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |