Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725527 | 0.69 | CYP3A4 (0.48) | IDO1CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL1771094 | 0.65 | — | — | |
| SCHEMBL31444208 | 0.64 | IDO1 (0.58) | IDO1CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL2564383 | 0.64 | IDO1 (0.47) | IDO1CYP3A4POLBSMN1; SMN2ASIC3 | |
| Hydrochloric Acid SCHEMBL27258266 | 0.62 | IDO1 (0.60) | IDO1CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL7194641 | 0.62 | IDO1 (0.59) | IDO1CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL509585 | 0.62 | HPGDS (0.44) | IDO1CYP3A4CYP2E1CYP2D6CYP2A6 | |
| SCHEMBL28243318 | 0.61 | IDO1 (0.50) | IDO1POLBSMN1; SMN2ASIC3CYP11B1 | |
| SCHEMBL12543941 | 0.60 | IDO1 (0.74) | IDO1CYP3A4MAPTPOLBSMN1; SMN2 | |
| SCHEMBL496675 | 0.60 | IDO1 (0.64) | IDO1CYP3A4CYP2E1CYP2D6CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212143-B2 | Small molecule inhibitors of protein kinases | LEVOLTA PHARMACEUTICALS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | LEVOLTA PHARMACEUTICALS, INC. | 2013-03-07 | — | — | US | disclosed |
| WO-2011139295-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | IMC BIOTECHNOLOGY, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | SYK, BTK, LCK | IDO1 1598/4885CYP3A4 4595/4885CYP2E1 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.