Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788084 | 1.00 | TP53 (0.35) | TP53KDM4EALDH1A1CYP3A4TSHR | |
| SCHEMBL22389045 | 0.91 | KDM4E (0.30) | KDM4E | |
| SCHEMBL22389044 | 0.90 | ALDH1A1 (0.38) | TP53KDM4EALDH1A1CYP3A4TSHR | |
| SCHEMBL21788095 | 0.83 | ADRB2 (0.36) | KDM4EALDH1A1CYP3A4TSHR | |
| SCHEMBL24117766 | 0.81 | KDM4E (0.35) | KDM4E | |
| SCHEMBL31621432 | 0.75 | KDM4E (0.52) | KDM4E | |
| SCHEMBL23482673 | 0.75 | KDM4E (0.32) | TP53KDM4ETSHR | |
| SCHEMBL21730064 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4TSHR | |
| SCHEMBL104741 | 0.75 | TSHR (0.35) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL21788081 | 0.75 | TSHR (0.35) | ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | TP53 321/4885KDM4E 4137/4885ALDH1A1 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.