Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25943291 | 0.88 | MAOA (0.46) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25949865 | 0.88 | MAOA (0.46) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25943144 | 0.88 | POLB (0.46) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25943145 | 0.87 | POLB (0.48) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25942916 | 0.87 | POLB (0.45) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25948964 | 0.85 | S1PR3 (0.45) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25949813 | 0.83 | ALOX5 (0.44) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25939012 | 0.83 | MAPT (0.54) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25938977 | 0.82 | MAPT (0.55) | MAOAMAOBKDM4ELMNAGAA | |
| SCHEMBL25938947 | 0.81 | S1PR3 (0.44) | MAOAMAOBKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |