Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.75 |
| ▸ | RARG | P13631 | 7/20 | 0.75 |
| ▸ | RARA | P10276 | 6/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 6/20 | 0.47 |
| ▸ | RXRB | P28702 | 4/20 | 0.47 |
| ▸ | RXRG | P48443 | 4/20 | 0.47 |
| ▸ | VDR | P11473 | 2/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666958 | 1.00 | RARB (0.75) | RARBRARGRARACYP3A4PTPN1 | |
| SCHEMBL10844561 | 0.93 | RARB (0.64) | RARBRARGRARACYP3A4PTPN1 | |
| SCHEMBL10844563 | 0.93 | RARB (0.64) | RARBRARGRARACYP3A4PTPN1 | |
| SCHEMBL10846838 | 0.88 | RARA (0.72) | RARBRARGRARARXRARXRB | |
| SCHEMBL10846840 | 0.88 | RARA (0.72) | RARBRARGRARARXRARXRB | |
| SCHEMBL14159976 | 0.86 | RARB (0.57) | RARBRARGRARACYP3A4PTPN1 | |
| SCHEMBL14159896 | 0.86 | RARB (0.57) | RARBRARGRARACYP3A4PTPN1 | |
| SCHEMBL156460 | 0.86 | RARB (1.00) | RARBRARGRARACYP3A4RXRA | |
| SCHEMBL10841477 | 0.86 | RARB (1.00) | RARBRARGRARACYP3A4RXRA | |
| SCHEMBL10842924 | 0.85 | RARB (0.55) | RARBRARGRARACYP3A4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011141928-A1 | PROCESS FOR THE PREPARATION OF HIGHLY PURE BEXAROTENE | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-11-17 | — | — | WO | disclosed |
| US-20090203720-A1 | Methods for inhibiting cell growth | ALLERGAN, INC. | 2009-08-13 | — | — | US | disclosed |
| WO-2005046726-A2 | COMBINATIONS FOR INHIBITING CELL GROWTH WHICH CONTAINS AN INHIBITOR OF HUMAN CK1 ALPHA ACTIVITY AND A RXR AGONIST | ALLERGAN, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| EP-0671005-A1 | RXR HOMODIMER FORMATION AND BRIDGED BICYCLIC AROMATIC COMPOUNDS AND THEIR USE IN MODULATING GENE EXPRESSION | LA JOLLA CANCER RESEARCH FOUNDATION (US) | 1995-09-13 | — | — | EP | disclosed |
| US-4578498-A | FOR SKIN DISORDERS; REDUCED TOXICITY | BASF AKTIENGESELLSCHAFT (DE) | 1986-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203720-A1 | Methods for inhibiting cell growth | CSNK1G1, CSNK1A1, CSNK2A1 | RARB 163/4885RARG 167/4885RARA 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.