Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25943967 | 0.93 | PRMT5 (0.51) | PRMT5WDR77AAK1RAD52POLB | |
| SCHEMBL25944000 | 0.88 | PRMT5 (0.40) | PRMT5WDR77RAD52P4HBMAPT | |
| SCHEMBL25942960 | 0.83 | KDM1A (0.41) | RAD52POLBGAAALOX5MEN1 | |
| SCHEMBL25943586 | 0.81 | RAD52 (0.46) | RAD52P4HBMAPTALOX5MEN1 | |
| SCHEMBL25948157 | 0.78 | PRMT5 (0.52) | PRMT5WDR77AAK1MEN1KMT2A | |
| SCHEMBL25943142 | 0.77 | ALOX5 (0.44) | MAPTGAAALOX5MEN1KMT2A | |
| SCHEMBL25944006 | 0.76 | ALOX5 (0.40) | RAD52P4HBMAPTGAAALOX5 | |
| SCHEMBL25943901 | 0.76 | RAD52 (0.46) | RAD52P4HBMAPTPOLBALOX5 | |
| SCHEMBL25946923 | 0.74 | RAD52 (0.47) | RAD52P4HBMAPTPOLBGAA | |
| SCHEMBL25946422 | 0.74 | RAD52 (0.49) | RAD52P4HBMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |