Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25942960 | 0.85 | KDM1A (0.41) | ALOX5MEN1KMT2AKDM4ELMNA | |
| SCHEMBL25943140 | 0.81 | ALOX5 (0.53) | ALOX5MEN1KMT2AKDM4ELMNA | |
| SCHEMBL25944005 | 0.77 | PRMT5 (0.51) | ALOX5MEN1KMT2AKDM4ELMNA | |
| SCHEMBL25943128 | 0.75 | AGTR1 (0.39) | ALOX5MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20618039 | 0.72 | KDM4E (0.40) | MEN1KMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL25943967 | 0.71 | PRMT5 (0.51) | ALOX5MEN1KMT2AKDM4ELMNA | |
| SCHEMBL17206150 | 0.70 | MAPT (0.45) | MEN1KMT2AKDM4ELMNASMN1; SMN2 | |
| SCHEMBL25942548 | 0.69 | ALOX5 (0.47) | ALOX5MEN1KMT2AKDM4ELMNA | |
| SCHEMBL257901 | 0.69 | LIPG (0.59) | TSHR | |
| SCHEMBL12997511 | 0.69 | LMNA (0.43) | MEN1KMT2AKDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |