Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25939083 | 0.93 | RAD52 (0.45) | RAD52ELANEKDM4EALDH1A1ALOX5 | |
| SCHEMBL25948561 | 0.90 | RAD52 (0.43) | RAD52ELANEPRMT5WDR77KDM4E | |
| SCHEMBL25939177 | 0.90 | RAD52 (0.43) | RAD52ELANEPRMT5WDR77KDM4E | |
| SCHEMBL25944271 | 0.89 | PRMT5 (0.43) | RAD52ELANEPRMT5WDR77KDM4E | |
| SCHEMBL25938805 | 0.89 | ALOX5 (0.43) | RAD52KDM4EALDH1A1ALOX5MEN1 | |
| SCHEMBL25944270 | 0.88 | RAD52 (0.41) | RAD52ELANEKDM4EALDH1A1ALOX5 | |
| SCHEMBL25948669 | 0.86 | KDM4E (0.44) | RAD52ELANEKDM4EALDH1A1ALOX5 | |
| SCHEMBL25944053 | 0.86 | RAD52 (0.43) | RAD52ELANEKDM4EALDH1A1ALOX5 | |
| SCHEMBL25948533 | 0.85 | METAP2 (0.43) | RAD52ELANEKDM4EALDH1A1ALOX5 | |
| SCHEMBL25948775 | 0.85 | ALOX5 (0.42) | RAD52ELANEKDM4EALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |