Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 15/20 | 0.71 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6072306 | 0.86 | PGR (0.58) | PGRPDK2PDK4PDE3BPDE3A | |
| SCHEMBL20252517 | 0.85 | PGR (0.53) | PGR | |
| SCHEMBL3518135 | 0.84 | PGR (1.00) | PGRPDE3BPDE3A | |
| SCHEMBL31020836 | 0.79 | PGR (0.48) | PGR | |
| SCHEMBL7371913 | 0.79 | PGR (0.48) | PGR | |
| SCHEMBL30018222 | 0.79 | PGR (0.48) | PGRPDK2 | |
| SCHEMBL9375907 | 0.77 | PGR (0.50) | PGR | |
| SCHEMBL3526703 | 0.77 | PGR (1.00) | PGR | |
| SCHEMBL19241067 | 0.77 | PGR (0.46) | PGR | |
| SCHEMBL11435723 | 0.76 | PGR (0.46) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147597-A2 | ALLOSTERIC STING MODULATORS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-08-03 | — | — | WO | disclosed |