Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAT2A | P31153 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944688 | 0.87 | KMT2A (0.57) | MEN1KMT2ATHRBSMN1; SMN2MAPT | |
| SCHEMBL25944690 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2ATHRBSMN1; SMN2MAPT | |
| SCHEMBL1719451 | 0.86 | MEN1 (0.60) | MEN1KMT2ATHRBSMN1; SMN2TP53 | |
| SCHEMBL2885250 | 0.84 | MEN1 (0.74) | MEN1KMT2ATHRBSMN1; SMN2TP53 | |
| SCHEMBL25946268 | 0.83 | ALDH1A1 (0.63) | KMT2ASMN1; SMN2TP53MAPTALDH1A1 | |
| SCHEMBL16244880 | 0.82 | ALDH1A1 (0.74) | MEN1KMT2ATHRBSMN1; SMN2TP53 | |
| SCHEMBL25944689 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2ATHRBSMN1; SMN2MAPT | |
| SCHEMBL6315596 | 0.79 | MEN1 (1.00) | MEN1KMT2ATHRBSMN1; SMN2TP53 | |
| SCHEMBL30657206 | 0.79 | MEN1 (1.00) | MEN1KMT2ATHRBSMN1; SMN2TP53 | |
| SCHEMBL25944691 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2ATHRBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |