Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAT2A | P31153 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944688 | 0.90 | KMT2A (0.57) | ALDH1A1LMNAPOLBMAPTNPSR1 | |
| SCHEMBL25944686 | 0.86 | MEN1 (0.65) | ALDH1A1LMNAPOLBMAPTKMT2A | |
| SCHEMBL25944689 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAPOLBMAPTNPSR1 | |
| SCHEMBL25942412 | 0.82 | TSHR (0.48) | ALDH1A1MAPTKMT2AMEN1GPR55 | |
| SCHEMBL25944691 | 0.81 | ALDH1A1 (0.49) | ALDH1A1LMNAPOLBMAPTNPSR1 | |
| SCHEMBL25944694 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAPOLBMAPTNPSR1 | |
| SCHEMBL25944381 | 0.80 | ATM (0.46) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL2883770 | 0.76 | RECQL (0.62) | ALDH1A1LMNAPOLBMAPTNPSR1 | |
| SCHEMBL25941571 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL1719451 | 0.75 | MEN1 (0.60) | ALDH1A1POLBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |