Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146047 | 0.90 | GRM2 (0.35) | GRIA2GRIN2ACHEK1FLT3DRD2 | |
| SCHEMBL30775960 | 0.79 | GRIA2 (0.30) | GRIA2GRIN2A | |
| SCHEMBL30775994 | 0.73 | TDP1 (0.43) | — | |
| SCHEMBL30410253 | 0.71 | ABHD6 (0.42) | — | |
| SCHEMBL25146035 | 0.70 | GRM2 (0.42) | GRIA2GRIN2ADRD2 | |
| SCHEMBL31532472 | 0.68 | DRD3 (0.33) | DRD2DRD3 | |
| SCHEMBL30408375 | 0.68 | MGLL (0.42) | — | |
| SCHEMBL25327092 | 0.67 | GRIA1 (0.33) | CHEK1FLT3 | |
| SCHEMBL31532468 | 0.65 | — | — | |
| SCHEMBL31104604 | 0.64 | CHEK1 (0.32) | CHEK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144160-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-03 | — | — | WO | disclosed |