Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.80 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881878 | 1.00 | RXFP1 (0.80) | RXFP1EPHX1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6835642 | 0.89 | RXFP1 (1.00) | RXFP1EPHX1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30064828 | 0.89 | RXFP1 (1.00) | RXFP1EPHX1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1900214 | 0.88 | RXFP1 (0.66) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5515068 | 0.82 | RXFP1 (0.59) | RXFP1EPHX1KMT2AMEN1ALDH1A1 | |
| SCHEMBL6694336 | 0.81 | RXFP1 (0.53) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL21387943 | 0.81 | RXFP1 (0.58) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL29408737 | 0.80 | RXFP1 (0.61) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL422636 | 0.80 | RXFP1 (0.61) | RXFP1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8923243 | 0.79 | ALDH1A1 (0.66) | RXFP1EPHX1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024099269-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF | 华东师范大学 | 2024-05-16 | — | — | WO | disclosed |
| CN-118026880-A | Aryl amide compound, pharmaceutical composition containing same and application thereof | 华东师范大学 | 2024-05-14 | — | — | CN | disclosed |
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |