SCHEMBL1900214

SCHEMBL1900214

CC(=O)Nc1cccc2c(NC(C)=O)cccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.66
KMT2A Q03164 2/20 0.65
MEN1 O00255 1/20 0.65
ALDH1A1 P00352 4/20 0.59
HPGD P15428 3/20 0.59
KDM4E B2RXH2 2/20 0.58
MAPT P10636 1/20 0.58
MAPK1 P28482 1/20 0.55
PKM P14618 1/20 0.53
POLB P06746 3/20 0.53
CASP6 P55212 1/20 0.53
CYP2C19 P33261 1/20 0.52
MAOA P21397 1/20 0.52
PARP14 Q460N5 2/20 0.51
ERCC1 P07992 1/20 0.51
FEN1 P39748 1/20 0.51
ERCC4 Q92889 1/20 0.51
GPR35 Q9HC97 1/20 0.50
GAA P10253 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21387943 0.92 RXFP1 (0.58) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL1805658 0.90 RXFP1 (0.56) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL1122552 0.90 TRPV1 (0.58) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL8923243 0.90 ALDH1A1 (0.66) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL18814229 0.88 RXFP1 (0.54) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL11315901 0.88 RXFP1 (0.54) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL3190678 0.88 RXFP1 (0.54) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL18814515 0.88 ALDH1A1 (0.62) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL3182003 0.88 RXFP1 (0.54) RXFP1KMT2AMEN1ALDH1A1HPGD
SCHEMBL31570817 0.88 RXFP1 (0.54) RXFP1KMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8377530-B2 Polyesters with low molecular weight additives for improved gas barrier properties EASTMAN CHEMICAL COMPANY (US) 2013-02-19 US claimed
US-20120199515-A1 POLYESTERS WITH LOW MOLECULAR WEIGHT ADDITIVES FOR IMPROVED GAS BARRIER PROPERTIES EASTMAN CHEMICAL COMPANY (US) 2012-08-09 US claimed
US-12034115-B2 Solid electrolyte composition, sheet for all-solid state secondary battery, electrode sheet for all-solid state secondary battery, and all-solid state secondary battery FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed
US-20240213479-A1 ELECTRODE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, ALL-SOLID STATE SECONDARY BATTERY, AND MANUFACTURING METHODS FOR ELECTRODE COMPOSITION, ELECTRODE SHEET FOR ALL-SOLID STATE SECONDARY BATTERY, AND ALL-SOLID STATE SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2024-06-27 US disclosed
US-8420295-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2013-04-16 US disclosed
US-8377530-B2 Polyesters with low molecular weight additives for improved gas barrier properties EASTMAN CHEMICAL COMPANY (US) 2013-02-19 US disclosed
US-8304168-B2 Lithographic printing plate precursor and process for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20120199515-A1 POLYESTERS WITH LOW MOLECULAR WEIGHT ADDITIVES FOR IMPROVED GAS BARRIER PROPERTIES EASTMAN CHEMICAL COMPANY (US) 2012-08-09 US disclosed
US-8097688-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2012-01-17 US disclosed
US-20110242191-A1 INK COMPOSITION, INKJET RECORDING METHOD AND PROCESS FOR PRODUCING MOLDED PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed
US-7985535-B2 Image-forming method and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-07-26 US disclosed
US-20080312217-A1 Organic Compounds NOVARTIS AG 2008-12-18 US disclosed
US-20080312217-A1 Organic Compounds NOVARTIS AG 2008-12-18 US disclosed
US-20080241739-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080194762-A1 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
WO-2007071396-A2 PYRAZINOYLGUANIDINE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY OR ALLERGIC CONDITIONS NOVARTIS AG (CH) 2007-06-28 WO disclosed
EP-0950669-B1 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080312217-A1 Organic Compounds TRPA1, TRPV1, CHRM1 RXFP1 176/4885KMT2A 3363/4885MEN1 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.