Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716875 | 1.00 | CYP2A13 (0.41) | CYP2A13SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL12422172 | 0.91 | CYP2A13 (0.46) | CYP2A13SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL12716769 | 0.91 | CYP2A13 (0.46) | CYP2A13SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL8378166 | 0.91 | CYP2A13 (0.46) | CYP2A13SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL7941629 | 0.82 | L3MBTL3 (0.41) | SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1HPGD | |
| SCHEMBL22180327 | 0.81 | CYP2A13 (0.42) | CYP2A13SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL27059565 | 0.80 | CYP2A13 (0.34) | CYP2A13SMN1; SMN2L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL12715134 | 0.79 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL12716792 | 0.79 | L3MBTL3 (0.34) | L3MBTL3L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL21363769 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223750-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND WHICH CONTAINS PYRIMIDINE | Asahi Kasei Pharma Corporation (JP) | 2023-08-09 | — | — | EP | disclosed |