Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25946554 | 0.88 | MAPK1 (0.53) | TBK1MAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL25946552 | 0.84 | TSHR (0.57) | TBK1MAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL25946556 | 0.82 | MAPK1 (0.45) | TBK1MAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL25946559 | 0.79 | TBK1 (0.44) | TBK1MAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL3500929 | 0.76 | KDM4E (0.67) | TBK1TSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL25946563 | 0.76 | MAPT (0.43) | MAPK1TSHRHSD17B10ALDH1A1ALOX5 | |
| SCHEMBL3500416 | 0.76 | HIF1A (0.57) | TBK1TSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL22620634 | 0.74 | PLK1 (0.56) | TBK1MAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL19084707 | 0.73 | TBK1 (0.45) | TBK1MAPK1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL21954283 | 0.73 | PTGS2 (0.64) | MAPK1TSHRALDH1A1ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |