Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TYR | P14679 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 5/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | BAX | Q07812 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20793944 | 1.00 | LMNA (0.64) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL22001052 | 1.00 | LMNA (0.64) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL3148686 | 0.94 | LMNA (0.73) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL23394825 | 0.89 | RAB9A (0.68) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL18934226 | 0.89 | RAB9A (0.68) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL12837118 | 0.89 | RAB9A (0.68) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL20780426 | 0.88 | LMNA (0.50) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL18678533 | 0.88 | ESR2 (0.56) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL20827662 | 0.88 | ELANE (0.55) | LMNATYRHPGDNPC1ALDH1A1 | |
| SCHEMBL1765333 | 0.87 | LMNA (0.84) | LMNATYRHPGDALDH1A1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986971-B1 | POLYMER-METAL JUNCTION COMPRISING PEEK-PEOEK COPOLYMER COMPOSITIONS, IN CONTACT WITH A METAL SUBSTRATE | SOLVAY SPECIALTY POLYMERS USA (US) | 2023-08-09 | — | — | EP | disclosed |