Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | LATS1 | O95835 | 5/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 4/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | AOC1 | P19801 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83998 | 0.83 | RPS6KA3 (0.54) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL25777526 | 0.81 | RPS6KA3 (0.45) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL10103687 | 0.80 | RPS6KA3 (0.41) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL13186489 | 0.80 | RPS6KA3 (0.41) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL1854863 | 0.79 | RPS6KA3 (0.47) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL22304214 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL14219235 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL30824555 | 0.79 | LOXL2 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL459016 | 0.79 | RPS6KA3 (0.47) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL1858846 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |