Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 6/20 | 0.35 |
| ▸ | LATS2 | Q9NRM7 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854863 | 1.00 | RPS6KA3 (0.47) | RPS6KA3LOXL2PDE4BPDE7ALATS1 | |
| SCHEMBL25208193 | 0.83 | RPS6KA3 (0.44) | RPS6KA3LOXL2PDE4BPDE7ALATS1 | |
| SCHEMBL83998 | 0.83 | RPS6KA3 (0.54) | RPS6KA3LOXL2LATS1LATS2TGFBR1 | |
| SCHEMBL25777526 | 0.81 | RPS6KA3 (0.45) | RPS6KA3LOXL2LATS1LATS2TGFBR1 | |
| SCHEMBL24037998 | 0.80 | LOXL2 (0.43) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL1858846 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2TGFBR1 | |
| SCHEMBL30824555 | 0.79 | LOXL2 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL22304214 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL14219235 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 | |
| SCHEMBL25947271 | 0.79 | RPS6KA3 (0.44) | RPS6KA3LOXL2LATS1LATS2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |