SCHEMBL25947306

SCHEMBL25947306

CCCCCCC(C)(I)CC

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 6/20 0.43
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
FDPS P14324 9/20 0.37
SMPD1 P17405 2/20 0.35
CES2 O00748 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL11683358 0.97 GGPS1 (0.41) GGPS1TSHRTHRBFDPS
SCHEMBL7872884 0.89
SCHEMBL10704293 0.86 GGPS1 (0.44) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL694544 0.79 GGPS1 (0.38) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL19322784 0.78 DNM1 (0.59) GGPS1TSHRFDPSSMPD1
SCHEMBL18214509 0.78 TSHR (0.47) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL10702811 0.78 TSHR (0.47) GGPS1TSHRTHRBFDPSSMPD1
SCHEMBL14607340 0.77
SCHEMBL16317972 0.77 GGPS1 (0.42) GGPS1FDPSSMPD1CES2LPAR1
SCHEMBL11687981 0.76 GGPS1 (0.44) GGPS1TSHRTHRBFDPSSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037462-B2 Polyolefin-polydiorganosiloxane block copolymer and method for the synthesis thereof DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-16 US disclosed
US-11814555-B2 Hot melt adhesive compositions containing polyolefin-polydiorganosiloxane copolymers and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
US-11702512-B2 Polysiloxane resin-polyolefin copolymer and methods for the preparation and use thereof DOW SILICONES CORPORATION (US) 2023-07-18 US disclosed