Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25947294 | 1.00 | HDAC4 (0.39) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL25334909 | 1.00 | HDAC4 (0.39) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL21399754 | 0.82 | POLB (0.38) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL2031804 | 0.79 | HDAC4 (0.46) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL31041077 | 0.79 | HDAC4 (0.46) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL27929404 | 0.79 | HDAC4 (0.46) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL30149221 | 0.76 | HDAC4 (0.44) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL31458614 | 0.73 | HDAC4 (0.42) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL1739391 | 0.71 | ALDH1A1 (0.40) | TSHRMAOAMAOBKDM1ACYP2C19 | |
| SCHEMBL11444336 | 0.71 | CYP11B2 (0.38) | CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142725-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGAND AND PALLADIUM COMPLEX THEREOF AS WELL AS PREPARATION METHOD AND USE THEREOF | 南开大学 | 2023-08-03 | — | — | WO | disclosed |