⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440232 | 1.00 | — | — | |
| SCHEMBL30007313 | 1.00 | — | — | |
| SCHEMBL20368987 | 0.87 | TSHR (0.48) | — | |
| SCHEMBL7046647 | 0.85 | TSHR (0.46) | — | |
| SCHEMBL11507723 | 0.83 | TSHR (0.44) | — | |
| SCHEMBL532758 | 0.83 | — | — | |
| SCHEMBL819217 | 0.82 | TSHR (0.37) | — | |
| SCHEMBL11162099 | 0.80 | — | — | |
| SCHEMBL214487 | 0.78 | — | — | |
| SCHEMBL573231 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270601-A1 | METHOD FOR ENZYMATIC SYNTHESIS OF BRIVARACETAM CHIRAL INTERMEDIATE | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2025-08-28 | — | — | US | claimed |
| CN-119776331-A | Nitrilase mutant and application thereof in synthesis of buvaracetam chiral intermediate | 浙江工业大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119464403-A | Buwa western medicine Synthesis method of tam | 浙江普洛家园药业有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-114908075-B | method for synthesizing buvaracetam chiral intermediate by enzymatic method | 浙江工业大学 | 2024-03-26 | — | — | CN | claimed |
| WO-2023184791-A1 | METHOD FOR ENZYMATIC SYNTHESIS OF BRIVARACETAM CHIRAL INTERMEDIATE | 浙江工业大学 | 2023-10-05 | — | — | WO | claimed |
| CN-116218823-A | Nitrilase mutant, engineering bacterium and application thereof in synthesis of (R) -3-cyanohexanoic acid | 浙江工业大学 | 2023-06-06 | — | — | CN | claimed |
| CN-114908075-A | Method for synthesizing brivaracetam chiral intermediate by enzyme method | 浙江工业大学 | 2022-08-16 | — | — | CN | claimed |
| CN-116218823-B | Nitrilase mutant, engineering bacterium and application thereof in synthesis of (R) -3-cyanohexanoic acid | 浙江工业大学 | 2026-04-28 | — | — | CN | disclosed |
| US-20250270601-A1 | METHOD FOR ENZYMATIC SYNTHESIS OF BRIVARACETAM CHIRAL INTERMEDIATE | ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) | 2025-08-28 | — | — | US | disclosed |
| CN-119776331-A | Nitrilase mutant and application thereof in synthesis of buvaracetam chiral intermediate | 浙江工业大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119614548-A | Be used for brivaracetam synthesis preparation method of immobilized nitrilase | 浙江普洛家园药业有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119462469-A | Buwa western medicine method for purifying tam | 浙江普洛家园药业有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119464403-A | Buwa western medicine Synthesis method of tam | 浙江普洛家园药业有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-114908075-A | Method for synthesizing brivaracetam chiral intermediate by enzyme method | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-114908075-A | Method for synthesizing brivaracetam chiral intermediate by enzyme method | 浙江工业大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-112151749-A | Electrochemical device and electronic device | 宁德新能源科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-104039764-B | The preparation method of octahydro-cyclopentano [c] pyrroles | 隆萨有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104039764-A | METHOD FOR PREPARATION OF OCTAHYDROCYCLOPENTA[C]PYRROLE | LONZA AG | 2014-09-10 | — | — | CN | disclosed |
| CN-102361888-B | Polymers functionalized with polycyano compounds | BRIDGESTONE CORP | 2013-11-20 | — | — | CN | disclosed |
| CN-102361888-A | Polymers functionalized with polycyano compounds | BRIDGESTONE CORP | 2012-02-22 | — | — | CN | disclosed |