Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GALK1 | P51570 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149033 | 0.81 | EP300 (0.59) | EP300LMNACYP2C9CYP2C19GALK1 | |
| SCHEMBL21378215 | 0.79 | EP300 (0.62) | EP300LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL16041820 | 0.79 | EP300 (0.62) | EP300LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL4926705 | 0.79 | EP300 (0.62) | EP300LMNACYP2C9CYP2C19FAAH | |
| SCHEMBL7792307 | 0.76 | EP300 (0.53) | EP300CYP3A4CYP2C9CYP2C19GALK1 | |
| SCHEMBL8099809 | 0.76 | EP300 (0.53) | EP300CYP3A4CYP2C9CYP2C19GALK1 | |
| SCHEMBL22227520 | 0.76 | EP300 (0.69) | EP300LMNACYP2C9CYP2C19 | |
| SCHEMBL2152202 | 0.75 | EP300 (0.50) | EP300 | |
| SCHEMBL4926648 | 0.73 | EP300 (0.55) | EP300LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4926646 | 0.73 | EP300 (0.55) | EP300LMNACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133271-A1 | BICYCLIC PHTHALAZIN-1(2H)-ONE DERIVATIVES AND RELATED USES | NodThera Limited (GB) | 2023-07-13 | — | — | WO | disclosed |