Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7792307 | 1.00 | EP300 (0.53) | EP300CYP3A4CYP2C9CYP2C19GLO1 | |
| SCHEMBL7149033 | 0.90 | EP300 (0.59) | EP300CYP2C9CYP2C19FAAHEPHX1 | |
| SCHEMBL21378215 | 0.89 | EP300 (0.62) | EP300CYP2C9CYP2C19FAAHEPHX1 | |
| SCHEMBL4926705 | 0.89 | EP300 (0.62) | EP300CYP2C9CYP2C19FAAHEPHX1 | |
| SCHEMBL16041820 | 0.89 | EP300 (0.62) | EP300CYP2C9CYP2C19FAAHEPHX1 | |
| SCHEMBL22227520 | 0.85 | EP300 (0.69) | EP300CYP2C9CYP2C19 | |
| SCHEMBL2152202 | 0.84 | EP300 (0.50) | EP300EPHX1 | |
| SCHEMBL4926646 | 0.82 | EP300 (0.55) | EP300CYP3A4CYP2C9CYP2C19FAAH | |
| SCHEMBL11717792 | 0.82 | GLO1 (0.56) | EP300CYP3A4CYP2C19GLO1FAAH | |
| SCHEMBL4926110 | 0.82 | GLO1 (0.56) | EP300CYP3A4CYP2C19GLO1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090975-A | Process for the preparation of 2-acetylcarboxylic esters | DSM FINE CHEMICALS AUSTRIA GMBH (AT) | 2000-07-18 | — | — | US | disclosed |