SCHEMBL4926705

SCHEMBL4926705

CCCCCCCC=C(C(=O)OC)C(=O)OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.62
EPHX1 P07099 1/20 0.42
FAAH O00519 5/20 0.42
TSHR P16473 1/20 0.41
TERT O14746 3/20 0.41
MAPT P10636 2/20 0.41
BLM P54132 2/20 0.41
HSD17B10 Q99714 2/20 0.41
FABP4 P15090 2/20 0.41
PTPN1 P18031 2/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
PPARA Q07869 2/20 0.41
GMNN O75496 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16041820 1.00 EP300 (0.62) EP300EPHX1FAAHTSHRTERT
SCHEMBL21378215 1.00 EP300 (0.62) EP300EPHX1FAAHTSHRTERT
SCHEMBL7149033 0.98 EP300 (0.59) EP300EPHX1FAAHTERTMAPT
SCHEMBL2152202 0.92 EP300 (0.50) EP300EPHX1TSHRPOLBF7
SCHEMBL4926648 0.89 EP300 (0.55) EP300EPHX1FAAHMAPTBLM
SCHEMBL4926646 0.89 EP300 (0.55) EP300EPHX1FAAHMAPTBLM
SCHEMBL8099809 0.89 EP300 (0.53) EP300EPHX1FAAHCYP2C9CYP2C19
SCHEMBL22227520 0.89 EP300 (0.69) EP300TERTMAPTBLMHSD17B10
SCHEMBL7792307 0.89 EP300 (0.53) EP300EPHX1FAAHCYP2C9CYP2C19
SCHEMBL11417749 0.85 EP300 (0.50) EP300EPHX1FAAHTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080305066-A1 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour GIVAUDAN SA (CH) 2008-12-11 US claimed
EP-1838278-A1 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR Givaudan SA (CH) 2007-10-03 EP claimed
WO-2006076821-A1 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR GIVAUDAN SA (CH) 2006-07-27 WO claimed
US-20240041752-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-02-08 US disclosed
EP-4288022-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2023-12-13 EP disclosed
WO-2022167123-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-08-11 WO disclosed
EP-4039244-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2022-08-10 EP disclosed
US-9585362-B2 Fragrance compounds GIVAUDAN S.A. (CH) 2017-03-07 US disclosed
US-9585362-B2 Fragrance compounds GIVAUDAN S.A. (CH) 2017-03-07 US disclosed
US-20160286753-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2016-10-06 US disclosed
US-20160286753-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2016-10-06 US disclosed
US-8575386-B2 Fragrance compounds GIVAUDAN S.A. (CH) 2013-11-05 US disclosed
US-8575386-B2 Fragrance compounds GIVAUDAN S.A. (CH) 2013-11-05 US disclosed
EP-2032516-B1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2012-09-26 EP disclosed
US-20090202464-A1 Fragrance Compounds GIVAUDAN S.A. (CH) 2009-08-13 US disclosed
US-20090202464-A1 Fragrance Compounds GIVAUDAN S.A. (CH) 2009-08-13 US disclosed
US-20080305066-A1 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour GIVAUDAN SA (CH) 2008-12-11 US disclosed
WO-2007143873-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2007-12-21 WO disclosed
EP-1838278-A1 2-C-SUBSTITUTED PROPANE-1,3-DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR Givaudan SA (CH) 2007-10-03 EP disclosed
WO-2006076821-A1 2 -C-SUBSTITUTED PROPANE-1, 3 -DICARBONYL COMPOUNDS AND THEIR USE IN NEUTRALISING MALODOUR GIVAUDAN SA (CH) 2006-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090202464-A1 Fragrance Compounds OR10J3, OR51E2, TAS2R5 EP300 929/4885EPHX1 2324/4885FAAH 1234/4885
US-20080305066-A1 2-C-Substituted Propane-1,3-Dicarbonyl Compounds and Their Use in Neutralising Malodour TYR, MAL2, ACMSD EP300 2098/4885EPHX1 1470/4885FAAH 1305/4885
US-20240041752-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS AOX1, TYR, OCIAD1 EP300 2974/4885EPHX1 217/4885FAAH 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.