Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949415 | 0.93 | HDAC2 (0.39) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25938740 | 0.86 | HDAC1 (0.41) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25949196 | 0.81 | ALOX5 (0.41) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25949074 | 0.80 | ALOX5 (0.46) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25948923 | 0.80 | RAD52 (0.38) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25949377 | 0.80 | RAD52 (0.48) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25938617 | 0.79 | HDAC2 (0.41) | ALOX5KDM4EKMT2AHDAC1HDAC2 | |
| SCHEMBL25951179 | 0.78 | ALOX5 (0.46) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25949367 | 0.77 | KDM4E (0.53) | ALOX5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL25938880 | 0.77 | HDAC2 (0.38) | KDM4EKMT2AHDAC1HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |