Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22861810 | 0.76 | GABRA1 (0.33) | — | |
| SCHEMBL10145476 | 0.74 | — | — | |
| SCHEMBL22573030 | 0.73 | SOS1 (0.35) | SLC6A2SLC6A4SLC6A3GAA | |
| SCHEMBL21672655 | 0.69 | — | — | |
| SCHEMBL17877153 | 0.67 | PRMT3 (0.32) | — | |
| SCHEMBL19501373 | 0.64 | — | — | |
| SCHEMBL12027238 | 0.64 | — | — | |
| SCHEMBL3519431 | 0.64 | — | — | |
| SCHEMBL2187502 | 0.64 | — | — | |
| SCHEMBL10197119 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555070-B1 | AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF | EPIZYME INC (US) | 2023-08-09 | — | — | EP | disclosed |