Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25942810 | 0.90 | ALOX5 (0.41) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25942835 | 0.88 | MAPT (0.52) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25942831 | 0.87 | ALDH1A1 (0.42) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25938883 | 0.87 | MAPT (0.53) | ALOX5KMT2AMEN1ALOX15MAPT | |
| SCHEMBL25942832 | 0.86 | TSHR (0.43) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25942630 | 0.86 | TSHR (0.43) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25942763 | 0.86 | KDM4E (0.43) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25942676 | 0.85 | TSHR (0.41) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25942764 | 0.85 | TSHR (0.41) | ALOX5KMT2AMEN1ALOX15TSHR | |
| SCHEMBL25949415 | 0.83 | HDAC2 (0.39) | ALOX5KMT2AMEN1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |