Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949199 | 0.86 | RXFP1 (0.65) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL24071023 | 0.86 | NPC1 (0.61) | NPC1RAB9AALDH1A1SMN1; SMN2KCNK3 | |
| SCHEMBL25949195 | 0.84 | MEN1 (0.66) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10055020 | 0.82 | NPC1 (0.94) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL22025454 | 0.82 | RXFP1 (0.70) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL25337572 | 0.81 | NPC1 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2KCNK3 | |
| SCHEMBL22065404 | 0.81 | RXFP1 (0.68) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4251968 | 0.81 | RXFP1 (0.94) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL30862297 | 0.81 | RXFP1 (0.94) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4248720 | 0.80 | RXFP1 (0.76) | RXFP1NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227447-A1 | BENZYLAMINE DERIVATIVES AS DDRS INHIBITORS | DDR2, DDR1, DDRGK1 | RXFP1 414/4885NPC1 2973/4885RAB9A 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.