Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 18/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22002162 | 0.88 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL22002064 | 0.80 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL25951059 | 0.79 | PRMT5 (0.32) | PRMT5WDR77 | |
| SCHEMBL22684565 | 0.78 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL25951122 | 0.77 | METTL3 (0.43) | PRMT5WDR77 | |
| SCHEMBL18026278 | 0.76 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL18009743 | 0.76 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL25949203 | 0.76 | PI4KA (0.47) | PRMT5WDR77 | |
| SCHEMBL18571700 | 0.76 | PI4KA (0.47) | PRMT5WDR77 | |
| SCHEMBL18571696 | 0.76 | PI4KA (0.47) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219496-A1 | NOVEL 6-6 BICYCLIC AROMATIC RING SUBSTITUTED NUCLEOSIDE ANALOGUES FOR USE AS PRMT5 INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |