Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355487 | 1.00 | KDM5A (0.43) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL25949435 | 0.98 | KDM5A (0.42) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL23960194 | 0.98 | KDM5A (0.41) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL25949109 | 0.95 | KDM5A (0.39) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL25010854 | 0.92 | KDM5A (0.37) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL25853402 | 0.87 | CA2 (0.45) | CA2FFAR4FFAR1LMNAGRIK1 | |
| SCHEMBL27334562 | 0.87 | DNM1 (0.38) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL24702742 | 0.87 | LCK (0.36) | KDM5APHF8KDM4CPLA2G1BPLA2G2A | |
| SCHEMBL24823958 | 0.84 | KDM5A (0.38) | KDM5APHF8KDM4CCA2FFAR4 | |
| SCHEMBL27383761 | 0.83 | CA2 (0.38) | KDM5APHF8KDM4CCA2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3920976-B1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS INC (US) | 2023-07-19 | — | — | EP | disclosed |