Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949314 | 0.94 | KDM4E (0.42) | KDM4EALDH1A1RAD52ELANEALOX5 | |
| SCHEMBL25948669 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1RAD52ELANEALOX5 | |
| SCHEMBL25939296 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1RAD52ELANEALOX5 | |
| SCHEMBL25948618 | 0.88 | ALOX5 (0.42) | KDM4EALDH1A1RAD52ELANEALOX5 | |
| SCHEMBL25948561 | 0.87 | RAD52 (0.43) | KDM4EALDH1A1RAD52ELANEALOX5 | |
| SCHEMBL25948646 | 0.86 | ALOX5 (0.44) | KDM4EALDH1A1RAD52ELANEALOX5 | |
| SCHEMBL25948837 | 0.86 | PKM (0.42) | KDM4EALDH1A1RAD52ALOX5MEN1 | |
| SCHEMBL25948760 | 0.85 | ALOX5 (0.42) | KDM4EALDH1A1RAD52ALOX5MEN1 | |
| SCHEMBL25951179 | 0.85 | ALOX5 (0.46) | KDM4EALDH1A1RAD52ALOX5MEN1 | |
| SCHEMBL25949213 | 0.84 | ALOX5 (0.41) | KDM4EALDH1A1RAD52ELANEALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209492-A1 | COMPOUND FOR TREATING THROMBOTIC DISEASES | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-07-12 | — | — | EP | disclosed |