SCHEMBL25950563

SCHEMBL25950563

c1ccc(-c2cccc(-c3ccccc3-c3nc(-c4cccc5c4sc4ccccc45)nc(-c4cccc5sc6ccccc6c45)n3)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.45
LIMK1 P53667 2/20 0.38
PARP14 Q460N5 1/20 0.35
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
MAPT P10636 1/20 0.34
MAP3K8 P41279 5/20 0.34
PRKDC P78527 4/20 0.33
GPR3 P46089 1/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
PIM3 Q86V86 1/20 0.32
F9 P00740 1/20 0.32
MAPK1 P28482 1/20 0.32
MAP2K1 Q02750 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21149219 0.94 ALOX5 (0.43) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL21149141 0.94 ALOX5 (0.43) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL23025066 0.93 ALOX5 (0.44) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL24682139 0.93 ALOX5 (0.43) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL26080437 0.93 ALOX5 (0.45) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL26080440 0.93 ALOX5 (0.45) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL25050524 0.93 ALOX5 (0.44) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL22085305 0.93 ALOX5 (0.43) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL25050473 0.93 ALOX5 (0.51) ALOX5LIMK1PARP14TNKSTNKS2
SCHEMBL24681385 0.92 ALOX5 (0.43) ALOX5LIMK1PARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-05 US disclosed
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-05 US disclosed
EP-4212526-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-07-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 ALOX5 579/4885LIMK1 279/4885PARP14 3217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.