Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 11/20 | 0.48 |
| ▸ | GRM5 | P41594 | 11/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15146264 | 0.85 | GRM1 (0.56) | GRM1GRM5PDK4GPR119NAMPT | |
| SCHEMBL29518255 | 0.85 | GRM1 (0.56) | GRM1GRM5PDK4GPR119NAMPT | |
| SCHEMBL31288575 | 0.81 | GRM1 (0.57) | GRM1GRM5PDK4GPR119NAMPT | |
| SCHEMBL16422787 | 0.81 | GRM1 (0.57) | GRM1GRM5PDK4GPR119NAMPT | |
| SCHEMBL30308912 | 0.81 | GRM1 (0.64) | GRM1GRM5PDK4GPR119NAMPT | |
| SCHEMBL30513853 | 0.81 | GRM1 (0.47) | GRM1GRM5PDK4GPR119SCN9A | |
| SCHEMBL25292398 | 0.80 | GRM1 (0.47) | GRM1GRM5PDK4GPR119SCN9A | |
| SCHEMBL29393087 | 0.80 | GRM1 (0.47) | GRM1GRM5PDK4GPR119SCN9A | |
| SCHEMBL30583878 | 0.80 | GRM1 (0.54) | GRM1GRM5PDK4GPR119 | |
| SCHEMBL24321922 | 0.80 | GRM1 (0.50) | GRM1GRM5PDK4GPR119WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227299-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |