Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 10/20 | 0.47 |
| ▸ | GRM5 | P41594 | 10/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518255 | 0.84 | GRM1 (0.56) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL15146264 | 0.84 | GRM1 (0.56) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL25952378 | 0.81 | GRM1 (0.48) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL31288575 | 0.81 | GRM1 (0.57) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL16422787 | 0.81 | GRM1 (0.57) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL7837556 | 0.79 | GRM1 (0.53) | GRM1GRM5PDK4PDE10ANAMPT | |
| SCHEMBL30308912 | 0.78 | GRM1 (0.64) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL25292398 | 0.78 | GRM1 (0.47) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL29393087 | 0.78 | GRM1 (0.47) | GRM1GRM5PDK4PDE10AGPR119 | |
| SCHEMBL24321526 | 0.77 | GRM1 (0.49) | GRM1GRM5PDK4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113816948-B | Condensed imidazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-08-11 | — | — | CN | disclosed |