Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21685133 | 0.88 | MAP4K1 (0.41) | MAP4K1PARP1ELANEPKM | |
| SCHEMBL21703398 | 0.83 | MAP4K1 (0.38) | MAP4K1PARP1ELANENOS1NOS2 | |
| SCHEMBL23452918 | 0.81 | MAP4K1 (0.41) | MAP4K1PARP1ELANENOS1NOS2 | |
| SCHEMBL25949955 | 0.76 | MAP4K1 (0.57) | MAP4K1 | |
| SCHEMBL21703101 | 0.76 | MAP4K1 (0.41) | MAP4K1PARP1ELANEPKM | |
| SCHEMBL23452892 | 0.75 | MAP4K1 (0.44) | MAP4K1ELANE | |
| SCHEMBL25949945 | 0.74 | MAP4K1 (0.71) | MAP4K1 | |
| SCHEMBL25950538 | 0.74 | MAP4K1 (0.46) | MAP4K1PKM | |
| SCHEMBL21685182 | 0.74 | MAP4K1 (0.38) | MAP4K1PARP1ELANE | |
| SCHEMBL21703352 | 0.72 | MAP4K1 (0.50) | MAP4K1PARP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219460-A1 | TRANSGLUTAMINASE 2 (TG2) INHIBITORS | Sitari Pharma, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |