SCHEMBL25954402

SCHEMBL25954402

c1ccc(-c2ccc3c(c2)oc2cc(-n4c5ccccc5c5cc(-c6nc(-c7ccccc7)nc(-c7ccc8c(c7)oc7ccccc78)n6)ccc54)ccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.37
MMP12 P39900 1/20 0.36
MMP13 P45452 1/20 0.36
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
HCRTR1 O43613 1/20 0.35
ATM Q13315 2/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
AHR P35869 1/20 0.34
TSPO P30536 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
CHEK2 O96017 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21883216 1.00 PTGER4 (0.37) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL24215974 0.98 PLA2G2A (0.37) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL25954394 0.98 PLA2G2A (0.37) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL21740697 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL21668882 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL25954400 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL21883294 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL25458850 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL24217314 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A
SCHEMBL25954399 0.98 L3MBTL1 (0.36) PTGER4MMP12MMP13PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149667-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2023-08-10 WO disclosed