Bucolome

Bucolome

SCHEMBL25956

CCCCC1C(=O)NC(=O)N(C2CCCCC2)C1=O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.57
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
CYP2C9 P11712 4/20 0.44
CYP2C19 P33261 4/20 0.44
MMP1 P03956 1/20 0.42
MMP3 P08254 1/20 0.42
MMP9 P14780 1/20 0.42
CYP3A4 P08684 3/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.42
POLB P06746 1/20 0.41
OPRM1 P35372 1/20 0.37
OPRK1 P41145 1/20 0.37
OPRL1 P41146 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1426458 0.94 ALDH1A1 (0.51) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL1426501 0.94 ALDH1A1 (0.51) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL17472455 0.91 ALDH1A1 (0.49) ALDH1A1KMT2ACYP2C9CYP2C19MMP1
SCHEMBL21834901 0.91 ALDH1A1 (0.48) ALDH1A1KMT2AKDM4EMEN1MAPT
Bucolome SCHEMBL28185473 0.86 ALDH1A1 (0.45) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL5271154 0.86 ALDH1A1 (0.61) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL94928 0.84 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTCYP2C9CYP2C19
Bucolome SCHEMBL1004750 0.83 ALDH1A1 (0.42) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL1426482 0.83 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTCYP2C9CYP2C19
Propane SCHEMBL9334285 0.83 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5497 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514478-B2 Bipolar nerve stimulation/monitoring cuff RETROPSOAS TECHNOLOGIES, LLC (US) 2026-01-06 US claimed
US-20250288236-A1 BIPOLAR NERVE STIMULATION/MONITORING CUFF RETROPSOAS TECHNOLOGIES, LLC 2025-09-18 US claimed
US-20250204843-A1 BIPOLAR NERVE STIMULATION/MONITORING CUFF RETROPSOAS TECHNOLOGIES, LLC 2025-06-26 US claimed
EP-4565123-A1 BIPOLAR NERVE STIMULATION/MONITORING CUFF RETROPSOAS TECHNOLOGIES, LLC (US) 2025-06-11 EP claimed
CN-119970173-A Arithmetic auxiliary positioning variable right angle triangle puncture frame 罗锋 2025-05-13 CN claimed
WO-2024220291-A1 BIPOLAR NERVE STIMULATION/MONITORING CUFF RETROPSOAS TECHNOLOGIES, LLC (US) 2024-10-24 WO claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
CN-116421403-A Cushion device for preventing subcutaneous effusion and application method thereof 周开甲 2023-07-14 CN claimed
CN-219184024-U High-precision lumbar puncture auxiliary positioner and device for side-center approach 福建医科大学附属协和医院 2023-06-16 CN claimed
CN-219070680-U Lumbar puncture auxiliary positioner and device for bypass median access 福建医科大学附属协和医院 2023-05-26 CN claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
WO-1997009973-A2 PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-03-20 WO claimed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO claimed
EP-0650361-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1995-05-03 EP claimed
WO-1994000130-A1 COMPOSITIONS FOR THE TREATMENT OF ARTHRITIS CONTAINING PHOSPHONATES AND NSAIDS PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 1994-01-06 WO claimed