SCHEMBL1426482

SCHEMBL1426482

CCC1C(=O)NC(=O)N(C2CCCCC2)C1=O.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.51
CYP2C9 P11712 4/20 0.51
CYP2C19 P33261 4/20 0.51
OPRM1 P35372 1/20 0.45
OPRK1 P41145 1/20 0.45
OPRL1 P41146 1/20 0.45
CYP3A4 P08684 3/20 0.44
GAA P10253 3/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.35
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL94928 0.98 ALDH1A1 (0.53) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
Propane SCHEMBL9334285 0.97 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
Hydrochloric Acid SCHEMBL9420413 0.95 ALDH1A1 (0.50) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
SCHEMBL21834901 0.86 ALDH1A1 (0.48) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
SCHEMBL17472455 0.86 ALDH1A1 (0.49) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
Bucolome SCHEMBL25956 0.83 ALDH1A1 (0.57) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
SCHEMBL9337201 0.83 ALDH1A1 (0.57) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
SCHEMBL1426501 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
SCHEMBL1426458 0.81 ALDH1A1 (0.51) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1
SCHEMBL7080822 0.79 OPRM1 (0.43) ALDH1A1CYP2C9CYP2C19OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9668943-B2 Dental conditioning composition KABUSHIKI KAISHA SHOFU (JP) 2017-06-06 US claimed
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH SHOFU INC. (JP) 2026-05-28 US disclosed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-4717249-A1 DENTAL COMPOSITION Shofu Inc. (JP) 2026-04-01 EP disclosed
EP-4717251-A2 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH Shofu Inc. (JP) 2026-04-01 EP disclosed
US-20260083642-A1 DENTAL COMPOSITION SHOFU INC (JP) 2026-03-26 US disclosed
US-12465559-B2 Fluorescent curable dental composition and cured product thereof KURARAY NORITAKE DENTAL INC. (JP) 2025-11-11 US disclosed
US-20250213434-A1 DENTAL CURABLE COMPOSITION HAVING FAVORABLE COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2025-07-03 US disclosed
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE KURARAY NORITAKE DENTAL INC. (JP) 2025-06-26 US disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-2108664-A1 COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
EP-2108663-A1 POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL Kuraray Medical Inc. (JP) 2009-10-14 EP disclosed
CN-101547930-A Novel compound, composition containing same, and method for producing polymerizable amide KURARAY MEDICAL INC (JP) 2009-09-30 CN disclosed
US-7488762-B2 Two paste-type glass ionomer cement KABUSHIKI KAISHA SHOFU (JP) 2009-02-10 US disclosed
US-20060247330-A1 Two paste-type glass ionomer cement KABUSHIKI KAISHA SHOFU (JP) 2006-11-02 US disclosed
EP-1066813-B1 Dental adhesive composition SHOFU KK (JP) 2004-10-06 EP disclosed
US-6583197-B1 Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent KABUSHIKI KAISHA SHOFU (JP) 2003-06-24 US disclosed
EP-1066813-A2 Dental adhesive composition KABUSHIKI KAISHA SHOFU (JP) 2001-01-10 EP disclosed
US-5707611-A Tooth surface treating agent KABUSHIKI KAISHA SHOFU (JP) 1998-01-13 US disclosed
EP-0702948-A1 TOOTH SURFACE TREATMENT KABUSHIKI KAISHA SHOFU (JP) 1996-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465559-B2 Fluorescent curable dental composition and cured product thereof BRD1, TBCA, BAZ1A ALDH1A1 1780/4885CYP2C9 2952/4885CYP2C19 1891/4885
US-20260144715-A1 DENTAL CURABLE COMPOSITION HAVING HIGH MECHANICAL STRENGTH CAD, SMCHD1, ITGA1 ALDH1A1 1523/4885CYP2C9 3247/4885CYP2C19 3054/4885
US-20250207005-A1 ADHESIVE COMPOSITION FOR STEREOLITHOGRAPHIC ARTICLE AND NON-STEREOLITHOGRAPHIC ARTICLE ACR, CAD, ALG3 ALDH1A1 111/4885CYP2C9 3805/4885CYP2C19 3099/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885CYP2C9 1741/4885CYP2C19 1770/4885
US-20260083642-A1 DENTAL COMPOSITION TAS2R42, COL2A1, TAS2R1 ALDH1A1 1319/4885CYP2C9 3641/4885CYP2C19 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.