⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562455 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL8370119 | 0.75 | — | — | |
| SCHEMBL134598 | 0.73 | — | — | |
| SCHEMBL4304729 | 0.71 | ALDH1A1 (0.48) | — | |
| SCHEMBL1708069 | 0.71 | — | — | |
| SCHEMBL23829778 | 0.71 | — | — | |
| SCHEMBL8968643 | 0.71 | — | — | |
| Trichloroacetic Acid SCHEMBL11719563 | 0.71 | ALDH1A1 (0.62) | — | |
| SCHEMBL9620703 | 0.71 | TSHR (0.44) | — | |
| SCHEMBL1708048 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113125627-B | Detection method for effective components of traditional Chinese medicine composition for treating nephropathy | 云南雷允上理想药业有限公司 | 2022-10-18 | — | — | CN | claimed |
| CN-114720213-A | A herba Lysimachiae Christinae control extract and its quality control method and application | 桂林三金药业股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-109771481-B | Quality detection method and application of traditional Chinese medicine composition for tonifying kidney and relaxing spine | 北京中研同仁堂医药研发有限公司 | 2022-02-22 | — | — | CN | claimed |
| CN-113125627-A | Detection method for effective components of traditional Chinese medicine composition for treating nephropathy | 云南雷允上理想药业有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-113030364-A | Method for detecting three-yellow particles | 江苏省中医院 | 2021-06-25 | — | — | CN | claimed |
| CN-114981257-B | Substituted pyrazolopiperidine carboxylic acids | 拜耳公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118084999-A | Beta-galactosidase-responded diethyl dithiocarbamic acid copper complex prodrug compound and application thereof | 中山大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-118091007-A | Thin layer identification method of pharbitis seed sample | 江阴天江药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20240109864-A1 | SUBSTITUTED PYRAZOLYL PIPERIDINE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | US | disclosed |
| CN-117777103-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-20240101528-A1 | SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-03-28 | — | — | US | disclosed |
| CN-117720520-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| US-5716929-A | THERAPY FOR INFLAMMATION, AUTOIMMUNE DISEASES | VERTEX PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| WO-1997049736-A2 | PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS | G.D. SEARLE AND CO. (US) | 1997-12-31 | — | — | WO | disclosed |
| US-5656627-A | USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE AND NEURODEGENERATIVE DISEASES | VERTEX PHARMACEUTICALS, INC. (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0784628-A1 | INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | Vertex Pharmaceuticals Incorporated (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1995035308-A1 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-12-28 | — | — | WO | disclosed |
| EP-0677043-A4 | — | — | 1995-11-22 | — | — | EP | disclosed |
| EP-0677043-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1994014775-A1 | PLATELET AGGREGATION INHIBITING COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |