Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547503 | 0.86 | ALDH1A1 (0.47) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10147928 | 0.79 | TSHR (0.45) | ALDH1A1MAPTL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL845794 | 0.77 | GPR35 (0.58) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3862305 | 0.76 | GPR35 (0.44) | ALDH1A1MEN1KMT2AMAPTHTT | |
| Nitric Acid SCHEMBL845820 | 0.75 | ALDH1A1 (0.55) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21712377 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL30612947 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL8155992 | 0.73 | MAPT (0.45) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20547453 | 0.71 | ALDH1A1 (0.49) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21712407 | 0.71 | NPC1 (0.39) | LMNAALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | disclosed |