Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446405 | 0.76 | CHRM2 (0.53) | BCHEACHEPLGGABRA1GABRG2 | |
| SCHEMBL10902517 | 0.67 | BCHE (0.65) | BCHEACHEMAOAMAOBPLG | |
| SCHEMBL8372303 | 0.65 | CHRM5 (0.52) | BCHEACHEPLGGABRA1GABRG2 | |
| SCHEMBL22731089 | 0.64 | BCHE (0.42) | BCHEACHEPLGGABRA1GABRG2 | |
| SCHEMBL181015 | 0.64 | SLC18A3 (0.61) | MAOAMAOBSLC18A3SIGMAR1MAPT | |
| SCHEMBL721717 | 0.63 | ACHE (1.00) | BCHEACHEMAOAMAOBSLC18A3 | |
| SCHEMBL23127814 | 0.63 | S1PR1 (0.46) | MAOAMAOBALDH1A1CHRM2CHRM4 | |
| SCHEMBL5585087 | 0.63 | BCHE (0.49) | BCHEACHEMAOAMAOBPLG | |
| SCHEMBL5584863 | 0.63 | BCHE (0.49) | BCHEACHEMAOAMAOBPLG | |
| Iodide SCHEMBL16799291 | 0.63 | SLC18A3 (0.59) | MAOAMAOBSLC18A3SIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566862-A1 | BENZOFURANYL ANALOGUES AS GPR119 MODULATORS | Bristol-Myers Squibb Company (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140161-A1 | BENZOFURANYL ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-11-10 | — | — | WO | disclosed |