⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25602225 | 1.00 | — | — | |
| SCHEMBL25514660 | 0.77 | NCF1 (0.32) | — | |
| SCHEMBL25072106 | 0.77 | — | — | |
| SCHEMBL22010941 | 0.77 | — | — | |
| SCHEMBL25040370 | 0.76 | ATM (0.30) | — | |
| SCHEMBL24114934 | 0.76 | ATM (0.30) | — | |
| SCHEMBL17780254 | 0.74 | IRAK1 (0.32) | — | |
| SCHEMBL17780245 | 0.74 | IRAK1 (0.32) | — | |
| SCHEMBL18968085 | 0.74 | IRAK1 (0.32) | — | |
| SCHEMBL21178192 | 0.69 | APLNR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146989-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |