Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297998 | 0.75 | ALDH1A1 (0.40) | ELANEPARP1NPC1CYP1A2 | |
| SCHEMBL21297984 | 0.73 | PARP1 (0.37) | ELANEPARP1NPC1CYP1A2ADORA3 | |
| SCHEMBL862362 | 0.69 | ELANE (0.47) | ELANEPARP1CYP1A2ADORA3ADORA2A | |
| SCHEMBL21297937 | 0.67 | — | — | |
| SCHEMBL30667298 | 0.66 | ELANE (0.44) | ELANEPARP1CYP1A2ADORA3ADORA2A | |
| SCHEMBL10147922 | 0.65 | ACHE (0.46) | ELANEPARP1CYP1A2 | |
| SCHEMBL21297990 | 0.64 | CYP1A2 (0.38) | ELANEPARP1CYP1A2 | |
| SCHEMBL21297982 | 0.64 | CYP1A2 (0.38) | ELANEPARP1NPC1CYP1A2ADORA3 | |
| SCHEMBL18596477 | 0.64 | CYP1A2 (0.48) | PARP1CYP1A2 | |
| SCHEMBL8404515 | 0.64 | ELANE (0.50) | ELANEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | disclosed |