Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.36 |
| ▸ | ABAT | P80404 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881431 | 0.88 | KDM4E (0.41) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL27935044 | 0.83 | XDH (0.59) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL132439 | 0.83 | XDH (0.59) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL31122716 | 0.80 | XDH (0.57) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| Water SCHEMBL36578 | 0.80 | XDH (0.57) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL14154067 | 0.78 | ERN1 (0.44) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL12687888 | 0.78 | SRC (0.47) | XDHPTGS2CYP3A4CYP2C9SRC | |
| SCHEMBL1056033 | 0.74 | XDH (0.52) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL1527073 | 0.74 | XDH (0.52) | XDHKDM4EPTGS2RAB9AALDH1A1 | |
| SCHEMBL30822600 | 0.74 | XDH (0.52) | XDHKDM4EPTGS2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219504-A1 | MACROCYCLIC TLR7 AGONIST, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Visonpharma Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |