Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599026 | 1.00 | DPP4 (0.44) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL31588855 | 0.90 | DPP4 (0.44) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL31598989 | 0.87 | TACR1 (0.48) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL30543781 | 0.87 | DPP4 (0.49) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL25185295 | 0.87 | DPP4 (0.49) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL25185296 | 0.87 | DPP4 (0.49) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL25185297 | 0.87 | DPP4 (0.49) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL25339963 | 0.85 | DPP4 (0.45) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL30543841 | 0.85 | DPP4 (0.45) | DPP4GPR119IDO1TDO2USP30 | |
| SCHEMBL31346176 | 0.84 | GPR119 (0.50) | DPP4GPR119USP30TACR1YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146785-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2023-08-03 | — | — | WO | disclosed |