Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346185 | 0.93 | GPR119 (0.54) | GPR119DPP4JAK2JAK1TACR1 | |
| SCHEMBL23751448 | 0.90 | GPR119 (0.59) | GPR119JAK2JAK1YAP1KDM4E | |
| SCHEMBL22750434 | 0.90 | GPR119 (0.59) | GPR119JAK2JAK1YAP1KDM4E | |
| SCHEMBL22750429 | 0.90 | GPR119 (0.59) | GPR119JAK2JAK1YAP1KDM4E | |
| SCHEMBL22750432 | 0.90 | GPR119 (0.59) | GPR119JAK2JAK1YAP1KDM4E | |
| SCHEMBL25339963 | 0.88 | DPP4 (0.45) | GPR119DPP4JAK2JAK1MMP13 | |
| SCHEMBL30543841 | 0.88 | DPP4 (0.45) | GPR119DPP4JAK2JAK1MMP13 | |
| SCHEMBL25340387 | 0.88 | DPP4 (0.45) | GPR119DPP4JAK2JAK1MMP13 | |
| SCHEMBL30543839 | 0.88 | DPP4 (0.45) | GPR119DPP4JAK2JAK1MMP13 | |
| SCHEMBL25957732 | 0.88 | GPR119 (0.50) | GPR119DPP4JAK2JAK1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746968-A1 | PYRROLIDINE COMPOUNDS LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024216-A1 | PYRROLIDINE COMPOUNDS Lp(a) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |