Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970988 | 0.85 | ATM (0.39) | KAT6AKAT8ATMCCR5OPRM1 | |
| SCHEMBL966336 | 0.79 | ATM (0.45) | ATMCCR5OPRM1OPRL1 | |
| SCHEMBL24449463 | 0.79 | THRA (0.39) | KAT6AKAT8ATMCCR5OPRM1 | |
| SCHEMBL24448730 | 0.79 | THRA (0.39) | KAT6AKAT8ATMCCR5OPRM1 | |
| SCHEMBL24449617 | 0.78 | KAT6A (0.34) | KAT6AKAT8ATMCCR5OPRM1 | |
| SCHEMBL969724 | 0.78 | ATM (0.47) | ATMCCR5 | |
| SCHEMBL965553 | 0.76 | ATM (0.50) | ATM | |
| SCHEMBL25957833 | 0.71 | KDM1A (0.44) | — | |
| SCHEMBL25961941 | 0.71 | KDM1A (0.44) | — | |
| SCHEMBL25957835 | 0.71 | HSD11B1 (0.38) | KAT6AKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | Epizyme, Inc. (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685732-B2 | MYST family histone acetyltransferase inhibitors | EP300, KAT2A, KAT6A | KAT6A 3/4885KAT8 6/4885ATM 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.